​​The NCID building is specially designed to ensure the safety of patients, staff and the community and to shoulder the outbreak response for Singapore.  The 330-bed facility has expansion capacity to accommodate more than 500 beds during an outbreak.  It contains a large screening centre, isolation and cohort wards, well-designed negative pressure rooms, as well as a high-level isolation unit to safely contain and manage high consequence pathogens.  As a self-contained facility, NCID is able to confine the treatment of infected patients to a single place and the entire building can be locked down during larger outbreaks for the safe management of highly infectious agents.

Situated at the heart of Health City Novena, NCID is well-connected to Tan Tock Seng Hospital, the Lee Kong Chian School of Medicine and the Ng Teng Fong Centre for Healthcare Innovation for better collaboration and more coordinated operations.