The Department of STI Control (DSC) of the NSC, runs the National STI Control Programme for the Ministry of Health. The department is located at Block 31 Kelantan Lane, Singapore 200031.

The DSC is the only public specialist STI facility in Singapore. It provides comprehensive medical, nursing, laboratory, education and counselling services at subsidised rates. It conducts research in laboratory diagnostics, clinical trials, as well as behavioural and social sciences related to STI/HIV. It also provides training for undergraduates, postgraduates and paramedical personnel.

Sexually Transmitted Infections (STIs) are part of the medical specialty of dermato-venereology.