This guide outlines the step-by-step process for Video Observed Therapy (VOT) used by the National Tuberculosis Care Centre to monitor tuberculosis medication adherence remotely. It details preparation requirements including dark plate, transparent cup, TB medicines, and Zoom app setup with proper camera positioning. The consumption phase involves showing medicine packets to nurses for verification, removing correct pill quantities, and demonstrating pill-by-pill consumption with mouth opening for confirmation. This telemedicine approach ensures proper medication compliance while allowing patients to take their TB treatment from home under professional supervision.