This guide educates patients about radiation dermatitis during head and neck radiation therapy, explaining the progression from low-grade changes like pinkish skin and itching to high-grade changes with broken, blistered skin. It provides comprehensive skin care instructions including using gentle moisturizers 2-4 times daily, avoiding sun exposure, taking lukewarm showers, and specific care for moist desquamation using damp towels with cool water, emphasizing when to seek medical help for fever or severe symptoms.