Nasopharyngeal Cancer (NPC)

Overview


Nasopharyngeal cancer, or nose cancer, is the most common head and neck cancer in Singapore. It is the 8th most common cancer in males in Singapore, accounting for 3.7% of all cancers in males from 2010 to 2014.1 (*Singapore Cancer Registry, Interim Annual Report 2015)


This cancer occurs at the back of the nose, just behind the opening that connects the nose to the ear.


 
 

Causes

  • Long-term consumption of preserved food
  • Virus infection (Epstein Barr virus)
  • Family history of nasopharyngeal cancer
Signs & Symptoms
  • Blood-stained saliva
  • Lymph gland enlargement in the neck
  • Nose blockage
  • Decreased hearing

Detection & Treatment

Your doctor will perform a nasoendoscopy procedure, where a fibreoptic camera is passed through your nose to obtain a view of nasopharynx.


Two types of investigations are required:

  • Biopsy of the back of the nose to determine the presence of cancer. This is done in the clinic.
  • Scans to determine the spread of the disease. Commonly-performed scans include:
    • Magnetic Resonance Imaging (MRI) scan of the nose and neck
    • Positron Emission Tomography (PET) scan to determine if the cancer has spread to the lungs, liver or bones

Treatment

The treatment of nasopharyngeal cancer depends on the stage of disease:

  • Early stage: Radiotherapy only

  • Advanced stage: Chemoradiotherapy

Care Management


 
Additional Resources