Overview
What is Myasthenia Gravis?
Myasthenia gravis (MG) is a condition which causes certain muscles to become tired and weak easily. The muscles controlling the movement of the eyeball and eyelids are commonly affected.
Causes
MG is an autoimmune condition. An autoimmune condition occurs when your body's immune system mistakenly attacks healthy tissue. In MG, the autoimmune antibodies (Acetylcholine receptor antibodies, AChRAb) attack the muscles. This interrupts the signals from the nerves to the muscles, leading to weakness of the muscles.
Normal Neuromuscular Junction

Myasthenia Gravis


Detection & Treatment
The treatment for MG is primarily medication to counter the effects of the autoimmune antibodies.
These medications include:
1. Pyridostigmine: This is the most commonly used medication.
2. Steroids: Steroids can be very effective, but long-term use may cause some side effects which include:
3. Steroid-sparing immunosuppression
Care Management
What is the outlook for this condition?
A proportion of patients may develop generalized MG. You should see your doctor immediately if you experience any of the following:
MG is a long-term condition which will need regular monitoring. However, with medication, most patients are able to continue having a good quality of life.
Specialties & Services