Specimen Stability (for laboratory use only)
Collection Container
Service Code:
Service code pending
Collection Instructions:
Please call the Anatomic Pathology Section (DID: 1602) to discuss with Pathologist on the appropriate specimen instruction.
Unacceptable Conditions:
N.A.
Specimen Stability:
Ambient
Blocks and slides: 10 years
Wet tissue: 2 months
Wet tissue: 2 months
Performance
Turn Around Time:
Up to 8 working days
Days Test Performed:
Testing Laboratory:
Diagnostic Molecular Oncology Centre (DMOC) via National University Hospital (NUH)
Clinical & Interpretative
Description:
This assay detects substitution of glutamic acid for valine at amino acid 600 (p.V600E) of the BRAF gene. This is the most common BRAF mutation in metastatic colorectal carcinoma, papillary thyroid carcinoma and melanoma.
Methodology:
In-house real-time Polymerase Chain Reaction (PCR)
Reference Interval:
See laboratory report
Critical Values:
N.A.
