Timothy-Barkham.jpg

Clinical Interests

Clinical and Laboratory aspects of Infection (Clinical Microbiology), Traveller’s Health and Vaccines

Languages

English
About

Adj A/Prof Barkham obtained his medical degree (MBBS) from the University of London. He undertook specialist training at St Thomas’ Hospital, London, UK, obtaining a MSc in Clinical Microbiology, a certificate of completion of specialist training, and membership of the Royal College of Pathologists. He has a Certificate in Travel Health, and Compressed Air Works.

He is a Senior Consultant in the Department of Laboratory Medicine at TTSH. He also practices in the Travellers Health and Vaccine Clinic at TTSH. He is heavily involved in education as an Adjunct Associate Professor (Adj A/Prof) at the National University of Singapore Yong Loo Lin School of Medicine (NUS YLL SoM) and is the Programme Director of the Microbiology Residency in Singapore. He currently serves as chairman of the NEA Bioethics Review Committee.

He received the Courage Medal in 2003 and the COVID Resilience Medal in 2023. His awards include the Digital Education Award (Team) 2021 (NUS YLL SoM), the TTSH Research Award for Impactful Collaboration in 2020 for the Development of a SARS-CoV-2 Assay, the NHG Outstanding Research Impact Award 2019 for international work on Streptococcus agalactiae, and the NUS Medicine Special Recognition Award for Academic Year 2017/2018.

Publications

1. Multifunctional Antimicrobial ofiber Dressings Containing ?-Polylysine for the Eradication of Bacterial Bioburden and Promotion of Wound Healing in Critically Colonized Wounds.

2. Co-infections of Tilapia Lake Virus, Aeromonas hydrophila and Streptococcus agalactiae in Farmed Red Hybrid Tilapia

3. Niche Specialization and Spread of Staphylococcus Capitis Involved in Neonatal Sepsis

4. Community-acquired Group B streptococcal meningitis in adults.

5. Molecular characterization and pathogenicity of Streptococcus agalactiae serotypes Ia ST7 and III ST283 isolated from cultured red hybrid tilapia in Malaysia

6. Rationalisation of Antifungal Properties of a-Helical Pore-Forming Peptide, Mastoparan B.

7. Characterisation of Salmonella Enteritidis ST11 and ST1925 Associated with Human Intestinal and Extra-Intestinal Infections in Singapore.

8. Escherichia coli BarA-UvrY regulates the pks island and kills Staphylococci via the genotoxin colibactin during interspecies competition.

9. Invasive Streptococcus agalactiae ST283 infection after fish consumption in two sisters, Lao PDR.

10. Heme cross-feeding can augment Staphylococcus aureus and Enterococcus faecalis dual species biofilms.

11. Structural insights into the interaction of antifungal peptides and ergosterol containing fungal membrane.

12. Bacterial diseases of tilapia, their zoonotic potential and risk of antimicrobial resistance

13. Fish-associated Streptococcus agalactiae ST283: first human cases reported from Malaysia

14. Disease development in red hybrid tilapia following single and co-infection with tilapia lake virus and Streptococcus agalactiae

15. Sequence Types and Antimicrobial Resistance Profiles of Salmonella Typhimurium in the Food Chain in Singapore.

16. Multilocus sequence typing database for Streptococcus agalactiae contains a spurious allele of the transketolase gene.

This page was last updated in 2026.