Rheumatology, Tan Tock Seng Hospital
A/Prof Madelynn Chan is Senior Consultant Rheumatologist at the Department of Rheumatology, Allergy & Immunology, Tan Tock Seng Hospital and Rheumatology Lead and Associate Professor (Clinical Practice) at Lee Kong Chian School of Medicine, Nanyang Technological University. A/Prof Chan graduated from the University of Western Australia and trained in Rheumatology at Royal Perth Hospital in Perth, Western Australia and the Royal National Hospital for Rheumatic Diseases in Bath, England. She was awarded her MD research thesis on Systemic Lupus Erythematosus by the University of Bath.
A/Prof Chan chairs the NHG Health Research Ethics Committee. Her research interests include musculoskeletal health services outcomes and systemic lupus erythematosus outcomes. She is a clinical research investigator at Tan Tock Seng Hospital and has experience in conducting clinical randomised controlled trials in rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and systemic lupus erythematosus.
Publications
1. Robust SNP-based prediction of rheumatoid arthritis through machine-learning-optimized polygenic risk score
2. COVID-19 infection in patients with systemic lupus erythematosus: Data from the Asia Pacific Lupus Collaboration.
3. Independent associations of lymphopenia and neutropenia in patients with systemic lupus erythematosus: a longitudinal, multinational study.
4. Colorimetric and fluorescent TRAP assays for visualising and quantifying fish osteoclast activity.
5. Not at target': prevalence and consequences of inadequate disease control in systemic lupus erythematosus-a multinational observational cohort study.
6. Montreal cognitive assessment as a screening instrument for cognitive impairment in systemic lupus erythematosus patients without overt neuropsychiatric manifestations.
7. Association of Modified Systemic Lupus Erythematosus Responder Index Attainment and Long-Term Clinical Outcomes: A Five-Year Prospective Study
8. Patterns of Medication Use in Systemic Lupus Erythematosus - A Multi-Centre Cohort Study.
9. SMART-SLE: serology monitoring and repeat testing in systemic lupus erythematosus - an analysis of anti-double-stranded DNA monitoring.
10. Impact of low disease activity, remission, and complete remission on flares following tapering of corticosteroids and immunosuppressive therapy in patients with systemic lupus erythematous: a multinational cohort study
11. Comparison of Attainment and Protective Effects of Lupus Low Disease Activity State in Patients With Newly Diagnosed Versus Established Systemic Lupus Erythematosus.
12. Sub-optimal use of anti-malarial therapy for SLE in the Asia Pacific region: observations from the Asia Pacific lupus cohort
13. Association of systemic lupus erythematosus standard of care immunosuppressants with glucocorticoid use and disease outcomes: a multicentre cohort study.
14. Characterisation and outcomes of different subsets of low disease activity states in patients with systemic lupus erythematosus.
15. Risk of flare and damage accrual after tapering glucocorticoids in modified serologically active clinically quiescent patients with systemic lupus erythematosus: a multinational observational cohort study.
16. Association of Lupus Low Disease Activity State And Remission With Reduced Organ Damage And Flare in Systemic lupus erythematosus Patients With High Disease Activity
17. Association of sustained lupus low disease activity state with improved outcomes in systemic lupus erythematosus: a multinational prospective cohort study.
