
Gemcitabine is a chemotherapy drug used to treat certain types of cancer such as bladder, pancreatic, lung, nasopharyngeal and breast cancer. It is often used in combination with other types of chemotherapy.
Gemcitabine is given via an injection into the vein, as an infusion (drip).
Inform your healthcare professional if:
- You are allergic to this medication or any of the other ingredients of this medication
- You are pregnant, planning to become pregnant, or breastfeeding
- You are taking any other medications, including supplements, traditional medications and herbal remedies.
-
Early side-effects
-
Nausea or vomiting may occur
- You may be given anti-vomiting medications, take them as directed to help prevent or decrease these side effects.
- Take small frequent meals and avoid strong smells which may trigger nausea.
-
Temporary flu-like symptoms (e.g. mild fever, joint and muscle ache, chills, fatigue, headache)
- You can take paracetamol to help with fever or muscle and joint aches.
-
Nausea or vomiting may occur
-
Delayed side-effects
-
A drop in blood cell counts. This may put you at a higher risk of infections, bleeding or bruising, or feeling tired.
- To reduce risks of getting an infection, practise good personal hygiene, avoid crowded places or people who are sick and avoid eating raw food
- To reduce risks of bleeding and bruising, do not pick your nose. Brush your teeth with a soft-bristled toothbrush.
- If you are feeling tired, do not drive or engage in activities that require concentration.
-
Diarrhea
- Drink at least two litres (8 cups) of fluids every day if you are having diarrhea
- Avoid milk, dairy products, high fibre food or spicy food if you are having diarrhea
-
Itchy rashes
- Inform your doctor or nurse if it occurs. Applying a steroid cream may help.
-
Water retention causing swelling of the lower limbs
- Elevating your legs on a foot stool, cushion or pillow may help to reduce the swelling.
-
Mild hair loss or thinning may begin several weeks after treatment
- Wear a wig or hat, and use a gentle shampoo
-
Lung problems
- Let your doctor know if you feel more breathless
-
A drop in blood cell counts. This may put you at a higher risk of infections, bleeding or bruising, or feeling tired.
- Fever of 38° C or higher
- Unusual bleeding, bruising or black tarry stools
- Severe skin rash or itching
- Persistent shortness of breath or difficulty breathing
Avoid taking traditional chinese medications (TCM) or ‘jamu’ when you are on this medication
Disclaimer
Please take note that the above is not a complete list of all possible side-effects. If you have any concerns about your medication or if you have other side-effects that you think are caused by this medication, please consult your doctor or pharmacist. If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.
This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (NHG Health, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.

