This guide explains the Self Administration of Medication (SAM) program that teaches patients and caregivers to manage their own medications while hospitalized to prepare for home care. It covers eligibility criteria excluding those with memory problems or self-harm risk, the five-step process including consent, education on the "5 Rights" of medication administration, supervised practice, independent administration, and discharge planning with follow-up calls, emphasizing benefits of independence, privacy, and reduced medication errors.