This comprehensive guide explains continuous elastomeric infusion pumps for delivering medications like antibiotics continuously through veins over 1-2 days. It covers pump components including balloon reservoirs, tubing, and plastic casing, plus proper care techniques for bathing, sleeping, and carrying. The resource provides detailed step-by-step instructions for pump changes including hand hygiene, medication verification, PICC line patency checks, and secure connection procedures. It addresses storage requirements at 2-8°C, transportation with ice packs, troubleshooting for leaks or disconnections, and emergency contact information for OPAT clinic support during office hours and after-hours situations.